Corticospinal - specific HCN expression in mouse motor cortex : I h - dependent 1 synaptic integration as a candidate microcircuit mechanism involved in motor 2 control 3 4 5
نویسندگان
چکیده
4 5 Patrick L. Sheets, Benjamin A. Suter, Taro Kiritani, C. Savio Chan, D. James Surmeier, 6 Gordon M. G. Shepherd 7 8 Author addresses: Department of Physiology, Feinberg School of Medicine, Northwestern 9 University, Chicago, IL, USA 10 11 Correspondence: Patrick L. Sheets, PhD, Dept Physiol, Morton 5-660, Northwestern University, 12 303 East Chicago Ave., Chicago, IL 60611; 312-503-0753; [email protected] 13 Number of figures: 12 14 Number of pages: 48 15 Abbreviated Title: Ih in corticospinal neurons 16 Key terms: HCN1, pyramidal neuron, motor cortex, corticospinal, corticostriatal 17 18 Articles in PresS. J Neurophysiol (July 27, 2011). doi:10.1152/jn.00232.2011
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Corticospinal-specific HCN expression in mouse motor cortex: I(h)-dependent synaptic integration as a candidate microcircuit mechanism involved in motor control.
Motor cortex is a key brain center involved in motor control in rodents and other mammals, but specific intracortical mechanisms at the microcircuit level are largely unknown. Neuronal expression of hyperpolarization-activated current (I(h)) is cell class specific throughout the nervous system, but in neocortex, where pyramidal neurons are classified in various ways, a systematic pattern of exp...
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